Asian markets mixed, yen claws back some losses

HONG KONG: Asian markets were mixed on Friday, with Tokyo dragged by a further strengthening in the yen, while the euro faced selling pressure following weak eurozone data.

Losses on Wall Street added to the gloom after disappointing US economic figures, while traders were casting an eye to a general election in Italy at the weekend.

Tokyo fell 0.50 per cent by the break, Hong Kong lost 0.85 per cent and Shanghai was off 0.16 per cent, but Sydney jumped 1.26 per cent and Seoul added 0.23 per cent.

While some markets were lifted by bargain hunting, sentiment was still weak after minutes from the US Federal Reserve's latest policy meeting that stoked fears it could end its huge monetary easing sooner than expected.

Japan's Nikkei was weighed as the yen rose against the dollar and euro, clawing back some of the massive losses it has seen in recent months.

In early Tokyo trade the dollar sat at 93.04 yen, compared with 93.11 yen in New York Thursday. However, the Japanese unit -- which has lost about 17 per cent against the greenback since November -- is much stronger than the 94.00 yen seen at the start of the month.

And the euro fetched 122.78 yen, against 122.81 yen, and well off the 125.50 yen earlier in the week.

The euro bought $1.3189, against $1.3188 in New York Thursday and well short of the $1.3350 on Monday.

The euro came under increased pressure after a leading eurozone growth indicator showed private business activity hit a two-month low in February.

The Purchasing Managers' Index published by London-based Markit fell to 47.3 in February from 48.6 the previous month.

The February figures contrasted sharply with an improvement in the previous three months, which saw it hit a 10-month high in January.

There is nervousness about Sunday's Italian election, which is too close to call and which markets have warned could send the economy back into crisis if there is no clear winner.

Some fear a return of former prime minister Silvio Berlusconi, which could lead to the dismantling of recent economic reforms that have helped draw the country back from economic crisis.

On Wall Street the Dow was down 0.34 per cent, the S&P 500 eased 0.63 per cent and the Nasdaq dropped 1.04 per cent after worse-than-expected US business activity data, while new claims for unemployment benefits rose last week.

Consumer prices also came in flat for a second month in a row in January, underscoring weak inflationary pressures in the world's number one economy.

Meanwhile, traders are becoming increasingly concerned about the lack of progress in Washington on a deal to avert the sequester, deep government spending cuts economists say will slow US growth.

Oil prices rose, with New York's main contract, light sweet crude for delivery in April gaining 17 cents to $93.01 a barrel and Brent North Sea crude for delivery in April adding 17 cents to $113.70.

Gold was at $1,581.30 at 0247 GMT, compared with $1,568.41 late Thursday.

- AFP/ck

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No specific intelligence on Hyderabad twin blasts, Sushilkumar Shinde says

NEW DELHI: Union home minister Sushilkumar Shinde on Friday visited the scene of the twin bomb blasts, which claimed 14 lives and injured over 100, along with Andhra Pradesh chief minister Kiran Kumar Reddy and other senior officials.
"The total dead are 14, total injured is 119. Out of this six are critical," Home minister Sushil Kumar Shinde said at a news conference.

"There was general alert out for the entire national. I don't think the police have failed," said Shinde told the media.

Shinde, who arrived here early Friday, drove to Dilsukhnagar and inspected the blast scene along with Andhra Pradesh governor ESL Narasimhan, chief minister Kiran Kumar Reddy, state home minister Sabita Indra Reddy and other officials.

Director general of police Dinesh Reddy briefed Shinde about the two near-simultaneous blasts in the crowded area.

No group has yet claimed responsibility.

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APNewsBreak: Govs to hear Oregon health care plan

SALEM, Ore. (AP) — Oregon Gov. John Kitzhaber will brief other state leaders this weekend on his plan to lower Medicaid costs, touting an overhaul that President Barack Obama highlighted in his State of the Union address for its potential to lower the deficit even as health care expenses climb.

The Oregon Democrat leaves for Washington, D.C., on Friday to pitch his plan that changes the way doctors and hospitals are paid and improves health care coordination for low income residents so that treatable medical problems don't grow in severity or expense.

Kitzhaber says his goal is to win over a handful of other governors from each party.

"I think the politics have been dialed down a couple of notches, and now people are willing to sit down and talk about how we can solve the problem" of rising health care costs, Kitzhaber told The Associated Press in a recent interview.

Kitzhaber introduced the plan in 2011 in the face of a severe state budget deficit, and he's been talking for two years about expanding the initiative beyond his state. Now, it seems he's found people ready to listen.

Hospital executives from Alabama visited Oregon last month to learn about the effort. And the U.S. Department of Health and Human Services announced Thursday that it's giving Oregon a $45 million grant to help spread the changes beyond the Medicaid population and share information with other states, making it one of only six states to earn a State Innovation Model grant.

Kitzhaber will address his counterparts at a meeting of the National Governors Association. His talk isn't scheduled on the official agenda, but a spokeswoman confirmed that Kitzhaber is expected to present.

"The governors love what they call stealing from one another — taking the good ideas and the successes of their colleagues and trying to figure out how to apply that in their home state," said Matt Salo, director of the National Association of Medicaid Directors.

There's been "huge interest" among other states in Oregon's health overhaul, Salo said, not because the concepts are brand new, but because the state managed to avoid pitfalls that often block health system changes.

Kitzhaber persuaded state lawmakers to redesign the system of delivering and paying for health care under Medicaid, creating incentives for providers to coordinate patient care and prevent avoidable emergency room visits. He has long complained that the current financial incentives encourage volume over quality, driving costs up without making people healthier.

Obama, in his State of the Union address this month, suggested that changes such as Oregon's could be part of a long-term strategy to lower the federal debt by reigning in the growing cost of federally funded health care.

"We'll bring down costs by changing the way our government pays for Medicare, because our medical bills shouldn't be based on the number of tests ordered or days spent in the hospital — they should be based on the quality of care that our seniors receive," Obama said.

The Obama administration has invested in the program, putting up $1.9 billion to keep Oregon's Medicaid program afloat over the next five years while providers make the transition to new business models and incorporate new staff and technology.

In exchange, though, the state has agreed to lower per-capita health care cost inflation by 2 percentage points without affecting quality.

The Medicaid system is unique in each state, and Kitzhaber isn't suggesting that other states should adopt Oregon's specific approach, said Mike Bonetto, Kitzhaber's health care policy adviser. Rather, he wants governors to buy into the broad concept that the delivery system and payment models need to change.

That's not a new theory. But Oregon has shown that under the right circumstances massive changes to deeply entrenched business models can gain wide support.

What Oregon can't yet show is proof the idea is working — that it's lowering costs without squeezing on the quality or availability of care. The state is just finishing compiling baseline data that will be used as a basis of comparison.

One factor driving the Obama administration's interest in Oregon's success is the president's health care overhaul. Under the Affordable Care Act, millions more Americans will join the Medicaid rolls after Jan. 1, and the health care system will have to be able to absorb the influx of patients in a logistically and financially sustainable way.

The federal government will pay 100 percent of the costs for those additional patients in the first three years before scaling back to 90 percent in 2020 and beyond.

"There are a lot of governors who are facing the same challenges we're facing in Oregon," Kitzhaber said. "They recognize that the cost of health care is something they're going to have to get their arms around."

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Arias Challenged On Pedophilia Claim

Accused murderer Jodi Arias was challenged today by phone records, text message records, and her own diary entries that appeared to contradict her claim that she caught her ex-boyfriend, Travis Alexander, looking at pictures of naked boys.

Arias had said during her testimony that one afternoon in January 2008, she walked in on Alexander masturbating to pictures of naked boys. She said she fled from the home, threw up, drove around aimlessly, and ignored numerous phone calls from Alexander because she was so upset at what she had seen.

The claim was central to the defense's accusation that Alexander was a "sexual deviant" who grew angry and abusive toward Arias in the months after the incident, culminating in a violent confrontation in June that left Alexander dead.

Arias claimed she killed him in self-defense. She could face the death penalty if convicted of murder.

Catching Up on the Trial? Check Out ABC News' Jodi Arias Trial Coverage

Today, prosecutor Juan Martinez, who has been aggressive in questioning witnesses throughout the trial, volleyed questions at her about the claim of pedophilia, asking her to explain why her and Alexander's cell phone records showed five calls back and forth between the pair throughout the day she allegedly fled in horror. Some of the calls were often initiated Arias, according to phone records.

Jodi Arias Doesn't Remember Stabbing Ex-Boyfriend Watch Video

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Arias on Ex-Boyfriend's Death: 'I Don't Remember' Watch Video

She and Alexander also exchanged text messages throughout the afternoon and evening at a time when Arias claims the pedophilia incident occurred. In those messages they discuss logistics of exchanging one another's cars that night. Alexander sends her text messages about the car from a church social event he attended that night that she never mentioned during her testimony.

Arias stuck by her claim that she saw Alexander masturbating to the pictures, and her voice remained steady under increasingly-loud questioning by Martinez.

But Martinez also sparred with Arias on the stand over minor issues, such as when he asked Arias detailed questions about the timing and order of events from that day and Arias said she could not remember them.

"It seems you have problems with your memory. Is this a longstanding thing? Since you started testifying?" Martinez asked.

"No it goes back farther than that. I don't know even know if I'd call it a problem," Arias said.

"How far back does it go? You don't want to call them problems, are they issues? Can we call them issues? When did you start having them?" he asked in rapid succession. "You say you have memory problems, that it depends on the circumstance. Give me the factors that influence that."

"Usually when men like you or Travis are screaming at me," Arias shot back from the stand. "It affects my brain, it makes my brain scramble."

"You're saying it's Mr. Martinez's fault?" Martinez asked, referring to himself in the third person.

"Objection your honor," Arias' attorney finally shouted. "This is a stunt!"

Timeline of the Jodi Arias Trial

Martinez dwelled at one point about a journal entry where Arias wrote that she missed the Mormon baptism of her friend Lonnie because she was having kinky sex with Alexander. He drew attention to prior testimony that she and Alexander used Tootsie Pops and Pop Rocks candy as sexual props.

"You're trying to get across (in the diary entry) that this involved a sexual liaison with Mr. Alexander right?" he asked. "And you're talking about Tootsie Pops and Pop Rocks?"

"That happened also that night," Arias said.

"You were there, enjoying it, the Tootsie Pops and Pop Rocks?" he asked again, prompting a smirk from Arias.

"I enjoyed his attention," Arias said.

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French general urges EU to equip "impoverished" Mali army

BAMAKO, Mali (Reuters) - The European Union should complement a mission to train Mali's army, routed by rebels last year, by providing equipment from uniforms to vehicles and communications technology, a French general said on Wednesday.

General Francois Lecointre, appointed to head the EU training mission to Mali (EUTM) that was formally launched this week, said in Bamako equipping the "very impoverished" and disorganized Malian army was as important as training it.

Europe, along with the United States, has backed the French-led military intervention in Mali which since January 11 has driven al Qaeda-allied Islamist insurgents out of the main northern towns into remote mountains near Algeria's border.

European governments have ruled out sending combat troops to join French and African soldiers pursuing the Islamist rebels.

But the EU is providing a 500-strong multinational training force that will give military instruction to Malian soldiers for an initial period of 15 months at an estimated cost of 12.3 million euros ($16.45 million).

While hailing what he called the EU's "courageous, novel, historic" decision to support Mali, Lecointre told a news conference the Malian army's lack of equipment was a problem.

"I know the Malian state is poor, but the Malian army is more than poor," the French general told a news conference, adding that it urgently needed everything from uniforms and weapons to vehicles and communications equipment.

Last year, when Tuareg separatist forces swelled by weapons and fighters from the Libyan conflict swept out of the northern deserts, a demoralized and poorly-led Malian army collapsed and fled before them, abandoning arms and vehicles.

Mali's military was further shaken by a March 22 coup by junior officers who toppled President Amadou Toumani Toure, sowing division among rival army factions. Islamist radicals allied to al Qaeda later hijacked the victorious Tuareg rebellion to occupy the northern half of the country.

In a fast-charging military campaign led by Paris, French and African troops have driven the jihadists out of principal northern towns like Gao and Timbuktu, and are fighting the rebels in the Adrar des Ifoghas mountains.

HUMAN RIGHTS INSTRUCTION

Flanked by Mali's armed forces chief, General Ibrahima Dembele, Lecointre said he was disappointed that a meeting of international donors last month pledged funds for an African military force, known as AFISMA, being deployed in Mali, but included "very few" contributions for the Malian army itself.

"The European Union needs to invest today in the equipping of the Malian army and not just in its training," the general said, adding he would make this point strongly in a report to EU member state representatives early next month.

Asked how much re-equipping the army would cost, he said it would be "much more" than the 12 million euros of EU financing for the training mission, but could not give a precise estimate.

Starting early in April, the EU mission will start instructing Malian soldiers with a plan to train four new battalions of 600-700 members each, formed from existing enlisted men and new recruits.

Lecointre said the EU training would include instruction in human rights. Demands for this increased after allegations by Malian civilians and international human rights groups that Malian soldiers were executing Tuaregs and Arabs accused of collaborating with Islamist rebels.

The European training contingent is drawn from a range of European countries, but the main contributors would be France, Germany, Italy, Spain and Britain, EUTM officers said.

Mali's army has received foreign training before - several battalions that fled before the rebels last year were trained by the U.S. military and the leader of the March 22 coup, Captain Amadou Sanogo, attended training courses in the United States.

Dembele said U.S. training failed to forge cohesion among Malian units and he hoped the EU training would achieve this.

The United States, which halted direct support for the Malian military after last year's coup, could eventually resume aid if planned national elections in July fully restore democracy to the West African country.

Washington is providing airlift, refuelling and intelligence support to the French-led military intervention in Mali. ($1 = 0.7479 euros)

(Reporting by Pascal Fletcher; Editing by Jason Webb)

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It's 'The Oscars', now officially

LOS ANGELES: They are the 85th Academy Awards, the climax of Hollywood's awards season, this coming weekend -- except officially they're not. This year, they've been rebranded to "The Oscars."

The Academy of Motion Picture Arts and Sciences (AMPAS), which organizes Tinseltown's biggest awards, did not confirm the change revealed by show co-producer Neil Meron, who said "85th Academy Awards" was too "musty."

But it seems it's true, for this year at least: references to Academy Awards and that it's the 85th show -- a significant anniversary, one might have thought -- quietly disappeared from official AMPAS materials a few weeks ago.

"We're rebranding it," Meron told entertainment news website TheWrap in an interview with co-producer Craig Zadan this week, days before Hollywood's finest take to the red carpet at the Dolby Theatre on Sunday.

"We're not calling it 'The 85th annual Academy Awards,' which keeps it mired somewhat in a musty way. It's called 'The Oscars'," he said, adding that he believed the new approach would continue in years to come.

An AMPAS spokeswoman declined to confirm the change, but said: "We use Academy Awards and the Oscars interchangeably. We'll begin considering next year's marketing campaign in the spring."

Last year's Oscars poster was quite clearly emblazoned with "The 84th Academy Awards." This year's shows a picture of smiling host Seth MacFarlane under "The Oscars," in gold.

The Oscars organizers are widely understood to be targeting a younger audience for their annual show -- and "Family Guy" creator MacFarlane could be part of that strategy.

Two years ago a clear get-the-young-viewers ploy, with actors James Franco and Anne Hathaway jointly fronting the show, was widely criticized, with Franco's wooden performance drawing particular scorn.

Last year Eddie Murphy was initially set to host but pulled out at the last minute after an embarrassing gay slur row involving one of the producers, and the Academy fell back on veteran Billy Crystal, who hosted for a ninth time.

- AFP/sf

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Railway Budget likely to announce 100 new trains

NEW DELHI: Railways is planning to introduce about 100 trains, including AC double deckers, new passenger services and extension of services to cater to the demands of various states in the Rail Budget 2013-14.

As far as rolling stock programme is concerned, the announcement will be made for manufacturing of 4200 new coaches including 600 LHB coaches in the Rail Budget.

While provision for manufacturing of 670 new locomotives including 20 LNG locos will be made, the budget will also account for manufacturing of about 16,000 new wagons.

"The focus of the Rail Budget this year is on providing more amenities to passengers. Attempts have been made to cater to the demands of all regions including Northeast as there were representations for new trains from various states," sources in railway ministry said.

While services of some express trains have been extended, frequency of certain popular trains have also been increased keeping the demand of people's representatives in mind.

"About 100 new trains will be announced in the budget," the sources said.

Last year, Railways had announced launching of 175 trains including passenger services.

Maintaining cleanliness and hygiene in trains and stations, providing quality linen, upgradation of fire-fighting arrangements and new facilities for differently abled persons are some of the measures likely to be announced by Railway Minister Pawan Kumar Bansal in his maiden budget speech on February 26.

The proposal to provide braille stickers inside coaches for assisting visually impaired passengers are among the measures likely to be announced by Bansal.

A total of 543 trains have been identified for providing on board house keeping scheme (OBHS) to keep toilets and coaches clean and hygienic.

Railways have also proposed to set up about 10 mechanised laundries to improve supply of clean and quality linens on trains.

New measures for fire suppression system in AC coaches and pantry cars, which are more fire prone, are likely to be announced in the Railway Budget.

Cash-strapped railways, which has sought Rs 38,000 crore as general budgetary support (GBS) from the Finance Ministry, is likely to get about Rs 28,000 crore for the next fiscal.

Last year, it had got Rs 24,000 crore as GBS.

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Scientists use 3-D printing to help grow an ear

WASHINGTON (AP) — Printing out body parts? Cornell University researchers showed it's possible by creating a replacement ear using a 3-D printer and injections of living cells.

The work reported Wednesday is a first step toward one day growing customized new ears for children born with malformed ones, or people who lose one to accident or disease.

It's part of the hot field of tissue regeneration, trying to regrow all kinds of body parts. Scientists hope using 3-D printing technology might offer a speedier method with more lifelike results.

If it pans out, "this enables us to rapidly customize implants for whoever needs them," said Cornell biomedical engineer Lawrence Bonassar, who co-authored the research published online in the journal PLoS One.

This first-step work crafted a human-shaped ear that grew with cartilage from a cow, easier to obtain than human cartilage, especially the uniquely flexible kind that makes up ears. Study co-author Dr. Jason Spector of Weill Cornell Medical Center is working on the next step — how to cultivate enough of a child's remaining ear cartilage in the lab to grow an entirely new ear that could be implanted in the right spot.

Wednesday's report is "a nice advancement," said Dr. Anthony Atala, director of the Institute for Regenerative Medicine at Wake Forest Baptist Medical Center, who wasn't involved in the new research.

Three-dimensional printers, which gradually layer materials to form shapes, are widely used in manufacturing. For medicine, Atala said the ear work is part of broader research that shows "the technology now is at the point where we can in fact print these 3-dimensional structures and they do become functional over time."

Today, people who need a new ear often turn to prosthetics that require a rod to fasten to the head. For children, doctors sometimes fashion a new ear from the stiffer cartilage surrounding ribs, but it's a big operation. Spector said the end result seldom looks completely natural. Hence the quest to use a patient's own cells to grow a replacement ear.

The Cornell team started with a 3-D camera that rapidly rotates around a child's head for a picture of the existing ear to match. It beams the ear's geometry into a computer, without the mess of a traditional mold or the radiation if CT scans were used to measure ear anatomy.

"Kids aren't afraid of it," said Bonassar, who used his then-5-year-old twin daughters' healthy ears as models.

From that image, the 3-D printer produced a soft mold of the ear. Bonassar injected it with a special collagen gel that's full of cow cells that produce cartilage — forming a scaffolding. Over the next few weeks, cartilage grew to replace the collagen. At three months, it appeared to be a flexible and workable outer ear, the study concluded.

Now Bonassar's team can do the process even faster by using the living cells in that collagen gel as the printer's "ink." The 3-D technology directly layers the gel into just the right ear shape for cartilage to cover, without having to make a mold first.

The next step is to use a patient's own cells in the 3-D printing process. Spector, a reconstructive surgeon, is focusing on children born without a fully developed external ear, a condition called microtia. They have some ear cartilage-producing cells in that tissue, just not enough. So he's experimenting with ways to boost those cells in the lab, "so we can grow enough of them from that patient to make an ear," he explained.

That hurdle aside, cartilage may be the tissue most amenable to growing with the help of 3-D printing technology, he said. That's because cartilage doesn't need blood vessels growing inside it to survive.

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Newtown Shooter Had Sensory Processing Disorder

From the time he was little, Adam Lanza couldn't bear to be touched. By middle school, the chaos and noise of large, bustling classrooms began to upset him. At 20, just before the Newtown shootings, he was isolated and, the world would later learn, disturbed.

All this was revealed in "Raising Adam Lanza," an investigative report by the Hartford Courant in partnership with the PBS news program FRONTLINE, which aired Tuesday night.

Before the age of 6, Lanza had been diagnosed with a controversial condition, "sensory integration disorder" -- now known as sensory processing disorder, according to the report.

Those with sensory processing disorder or SPD may over-respond to stimuli and find clothing, physical contact, light, sound or food unbearable. They may also under-respond and feel little or no reaction to pain or extreme hot and cold. A third form involves sensory motor problems that can cause weakness and clumsiness or delay in developing motor skills.

In Photos: Sandy Hook Elementary School Shooting, Mourning

Whether SPD is a distinct disorder or a collection of symptoms pointing to other neurological deficits, most often anxiety or attention-deficit hyperactivity disorder (ADHD), has been debated by the medical community for more than two decades.

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No one will know why the withdrawn Lanza shot his mother four times in her own bed, then went to Sandy Hook Elementary School to slaughter six women and 20 first-graders before taking his own life on Dec. 14, 2012.

But this report, the most detailed account to date on his troubled life, paints a picture of a child coping with special needs and a mother, "devoted but perhaps misguided," struggling unsuccessfully to help.

"The most surprising thing for me was this sort of inwardness of Adam, a world view of someone that was afraid of the world," said show producer Frank Koughan. "He just reacted badly to the whole world and didn't want to be part of it. He was not some violent monster, except on one particular day, when he was exceedingly monstrous."

The investigative team interviewed family and friends of the shooter's parents, Nancy and Peter Lanza, and reviewed a decade's worth of messages and emails from his mother to close friends, describing her son's socially awkward behavior.

"Adam was a quiet kid. He never said a word," Marvin LaFontaine, a friend of Nancy Lanza, told them. "There was a weirdness about him and Nancy warned me once at one of the Scout meetings … 'Don't touch Adam.' She said he just can't stand that. He'd become teary-eyed and I think he would run to his mother."

In 1998, the Lanzas left their home in New Hampshire for Connecticut with Adam, who had already been diagnosed with the sensory disorder and was "coded" with an individual education plan, according to a family member who did not want to be identified by FRONTLINE.

"It was somebody well-placed who was completely in a position to know," said Koughan, 45, a veteran journalist who produced the film, "Drop-Out Nation."

Lanza didn't recognize pain, another feature of some types of SPD. He couldn't cope with loud noise, confusion or change, which would cause him to "shut down," according to the report.

"He'd almost go into a catatonic kind of state, which is another reason why in hindsight, he didn't seem like a threat to anybody," said Koughan. "He didn't lash out or beat up kids. He went within himself, until one day he didn't."

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Syria "Scud-type" missile said to kill 20 in Aleppo

AMMAN (Reuters) - A Syrian missile killed at least 20 people in a rebel-held district of Aleppo on Tuesday, opposition activists said, as the army turns to longer-range weapons after losing bases in the country's second-largest city.

The use of what opposition activists said was a large missile of the same type as Russian-made Scuds against an Aleppo residential district came after rebels overran army bases over the past two months from which troops had fired artillery.

As the uprising against President Bashar al-Assad, now a civil war, nears its two-year mark, rebels also landed three mortar bombs in the rarely-used presidential palace compound in the capital Damascus, opposition activists said on Tuesday.

The United Nations estimates 70,000 people have been killed in the conflict between largely Sunni Muslim rebels and Assad's supporters among his minority Alawite sect. An international diplomatic deadlock has prevented intervention, as the war worsens sectarian tensions throughout the Middle East.

A Russian official said on Tuesday that Moscow, which is a long-time ally of Damascus, would not immediately back U.N. investigators' calls for some Syrian leaders to face the International Criminal Court for war crimes.

Moscow has blocked three U.N. Security Council resolutions that would have increased pressure on Assad.

Casualties are not only being caused directly by fighting, but also by disruption to infrastructure and Syria's economy.

An estimated 2,500 people in a rebel-held area of northeastern Deir al-Zor province have been infected with typhoid, which causes diarrhea and can be fatal, due to drinking contaminated water from the Euphrates River, the World Health Organization (WHO) said on Tuesday.

"There is not enough fuel or electricity to run the pumps so people drink water from the Euphrates which is contaminated, probably with sewage," the WHO representative in Syria, Elisabeth Hoff, told Reuters by telephone.

The WHO had no confirmed reports of deaths so far.

BURIED UNDER RUBBLE

In northern Aleppo, opposition activists said 25 people were missing under rubble of three buildings hit by a several-meter-long missile. They said remains of the weapon showed it to be a Scud-type missile of the type government forces increasingly use in Aleppo and in Deir a-Zor.

NATO said in December Assad's forces fired Scud-type missiles. It did not specify where they landed but said their deployment was an act of desperation.

Bodies were being gradually dug up, Mohammad Nour, an activist, said by phone from Aleppo.

"Some, including children, have died in hospitals," he said.

Video footage showed dozens of people scouring for victims and inspecting damage. A body was pulled from under collapsed concrete. At a nearby hospital, a baby said to have been dug out from wreckage was shown dying in the hands of doctors.

Reuters could not independently verify the reports.

Opposition activists also reported fighting near the town of Nabak on the Damascus-Homs highway, another route vital for supplying forces in the capital loyal to Assad, whose family has ruled Syria since the 1960s.

Rebels moved anti-aircraft guns into the eastern Damascus district of Jobar, adjacent to the city centre, as they seek to secure recent gains, an activist said.

"The rebels moved truck-mounted anti-aircraft guns to Jobar and are now firing at warplanes rocketing the district," said Damascus activist Moaz al-Shami.

Russian Deputy Foreign Minister Gennady Gatilov told a news conference a U.N. war crimes report, which accuses military leaders and rebels of terrorizing civilians, was "not the path we should follow ... at this stage it would be untimely and unconstructive."

Syria is not party to the Rome Statute that established the ICC and the only way the court can investigate the situation is if it receives a referral from the Security Council, where Moscow is a permanent member.

(Writing by Oliver Holmes; Editing by Jason Webb)

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